Testing for CYP2C9 Before Anticoagulant Therapy

approach to antiplatelet and anticoagulant therapy before endoscopic procedures

the use of anticoagulant and antiplatelet agents has become more prevalent during the past decades. these drugs may potentially cause gastrointestinal (gi) bleeding. thus, there is an increasing need for gi endoscopy in patients who take these medications. in patients who take anticoagulant and antiplatelet agents, the appropriate conditions under which endoscopic procedures should be performed...

The role of CYP2C9 gene polymorphisms on anticoagulant therapy after heart valve replacement.

OBJECTIVE The aim of the present study was to investigate the role of CYP2C9 gene polymorphisms after heart valve replacement in a group of patients on warfarin therapy. MATERIALS AND METHODS The study population consisted of 74 patients with heart valve replacement. Peripheral blood was collected into evacuated tubes containing EDTA, and DNA was extracted from circulating leukocytes by using...

Androgen therapy: testing before prescribing and monitoring during therapy.

OBJECTIVE To explore the extent to which biochemical testing is used to diagnose androgen deficiency before initiating treatment and to learn whether recommendations for clinical monitoring of men taking androgen therapy are being followed. DESIGN Population-based retrospective cohort study. SETTING Winnipeg, Man. PARTICIPANTS A total of 902 men who filled at least 2 prescriptions for and...

The Case for Anticoagulant Therapy

PERHAPS it is best to introduce this discussion with a few general statements to clarify the position which we have maintained throughout the past years. We have held that anticoagulant therapy for myocardial infarction does not constitute tlhe ultimate, the comprehensive, or even an entirely satisfactory form of therapy for this condition. If research directed at the prevention or reversal of ...

Audit of anticoagulant therapy.